That route looks pretty good! The only reason I took interstates on my trip is I was on a time crunch and being on a sportbike, I was wanting to cover as much ground as quickly as possible to and from. As far as the actual PCH, I don't think it will matter much going north or south. Probably would be better going south though I would imagine, due to the fact that opposite traffic won't be between you and the ocean for better sights, or needing to cross the road if you want to stop for pictures etc. The only thing I noticed is, you missed a little stretch of hwy 1 just north of SF. the 101 right there is pretty much like being on I25 and always heavy in traffic. Also, I second taking Mulholland if you're going down that far anyway. Something I wasn't able to do.