I've had a set of the Pirelli Scorpion Trails on the Multi since it was new. No complaints on the street, after about 4800 miles. They were a little flat spotted in the rear, but still had probably 1000 more miles before hitting the tread wear indicators.
Yesterday, I went out on my first dirt road on this bike; it was the 2 miles or so of dirt on the 285 side of Guanella pass. And wouldn't you know, the tire got punctured (I think from a rock), and slow leaked down to flat over the next half hour or so. Ugh.
I was actually planning to buy another set of these prior to this...but after this incident, and having found a thread on a Ducati forum talking about how puncture prone they are, I'm out. Switching to a set of Pilot Road 3's tomorrow. Hoping they'll be ok for the occasional dirt road...